Standard

Height

MIR4744 · rs12456845

Where this position leads

Condition: Height

rs12456845 Condition: Height Height Condition rs12456845 rs12456845 MIR4744

What the study found

Who was studied 4,080,687 European ancestry individuals; replicated in 49,160 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.049 lower (95% confidence interval 0.046-0.052); p = 4 × 10−217.

How common The C allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 18, band 18q21.1 — in a non-coding transcript of MIR4744.

What each result means

C/C Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Questions about rs12456845

What is rs12456845?

rs12456845 is a single position in the genome, in or near the MIR4744 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12456845 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs12456845 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12456845 come from?

GWAS Catalog, Nature 2022, PMID:36224396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs12456845). MyGeneLog™. https://www.mygenelog.com/variants/rs12456845

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