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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,915 Chinese ancestry individuals; replicated in 1,299 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.153 lower (95% confidence interval 0.11-0.2); p = 2 × 10−11.
How common The A allele had a frequency of about 48% in the people studied.
Where it sits Chromosome 17, band 17p11.2 — between genes, 41.3 kb from MTCO3P13.
What each result means
A/ATwo copies of the version the research linked to Saliva microbiota abundance (Eggerthia). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Saliva microbiota abundance (Eggerthia). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Saliva microbiota abundance (Eggerthia). This is the starting point the study compared everyone against.
Cell discovery · 2021 · PMID 34873157 · open access
Questions about rs12453667
What is rs12453667?
rs12453667 is a single position in the genome, in or near the near MTCO3P13 gene. Published research associates it with saliva microbiota abundance (eggerthia). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12453667 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12453667 come from?
GWAS Catalog, Cell discovery 2021, PMID:34873157. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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