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Free cholesterol in small LDL (UKB data field 23549)

EFCAB13-DT · rs12452315

What the study found

Who was studied 88,329 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.034 higher (95% confidence interval 0.025-0.043); p = 8 × 10−13.

How common The C allele had a frequency of about 49% in the people studied.

Where it sits Chromosome 17, band 17q21.32 — in an intron of EFCAB13-DT.

What each result means

A/A No copy of the version the research linked to Free cholesterol in small LDL (UKB data field 23549). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Free cholesterol in small LDL (UKB data field 23549). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Free cholesterol in small LDL (UKB data field 23549). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12452315

What is rs12452315?

rs12452315 is a single position in the genome, in or near the EFCAB13-DT gene. Published research associates it with free cholesterol in small ldl (ukb data field 23549). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12452315 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12452315 come from?

GWAS Catalog, Biological psychiatry 2023, PMID:36764567. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Free cholesterol in small LDL (UKB data field 23549) (rs12452315). MyGeneLog™. https://www.mygenelog.com/variants/rs12452315

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