Sensitive

Prostate cancer

NTN1 · rs12449664

Where this position leads

Condition: Prostate Cancer

rs12449664 Condition: Prostate Cancer Prostate Cancer Condition rs12449664 rs12449664 NTN1

What the study found

Who was studied 961 Taiwanese ancestry cases, 3,792 Taiwanese ancestry controls.

The effect Each copy of the A allele carried 226.90 times the odds of Prostate cancer (95% confidence interval 47.75-1078.26); p = 9 × 10−12.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in an intron of NTN1.

What each result means

A/A Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
Source

Questions about rs12449664

What is rs12449664?

rs12449664 is a single position in the genome, in or near the NTN1 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12449664 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs12449664 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12449664 come from?

GWAS Catalog, Cancer medicine 2026, PMID:42415294. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs12449664). MyGeneLog™. https://www.mygenelog.com/variants/rs12449664

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