0 423228123120Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 3,584 Latino individuals; replicated in 931 Latino individuals.
The effect
Each copy of the A allele shifted the measure 4.51 higher; p = 4 × 10−8.
How common The A allele had a frequency of about 65% in the people studied.
Where it sits Chromosome 16, band 16q24.2 — in an intron of ZNF469.
What each result means
A/ATwo copies of the version the research linked to Central corneal thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Central corneal thickness. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Central corneal thickness. This is the starting point the study compared everyone against.
rs12448211 is a single position in the genome, in or near the ZNF469 gene. Published research associates it with central corneal thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12448211 linked to?
On MyGeneLog this position is linked to Central Corneal Thickness. The research behind each link, and its sources, are set out on that condition page.
Does having rs12448211 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12448211 come from?
GWAS Catalog, Hum Mol Genet 2016, PMID:28171582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 423228123120Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Central corneal thickness (rs12448211). MyGeneLog™. https://www.mygenelog.com/variants/rs12448211