Standard

Central corneal thickness

ZNF469 · rs12447690

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Central corneal thickness compared to the general population. (GWAS Catalog, PLoS Genet 2010, PMID:20485516)

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Central corneal thickness. (GWAS Catalog, PLoS Genet 2010, PMID:20485516)

T/T Published research associates this genotype with typical/baseline likelihood of Central corneal thickness — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2010, PMID:20485516)

Source: GWAS Catalog, PLoS Genet 2010, PMID:20485516

Questions about rs12447690

What is rs12447690?

rs12447690 is a single position in the genome, in or near the ZNF469 gene. Published research associates it with central corneal thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12447690 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12447690 come from?

GWAS Catalog, PLoS Genet 2010, PMID:20485516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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