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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 58,701 Korean ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.72 higher (95% confidence interval 0.52-0.92); p = 1 × 10−12.
Where it sits Chromosome 16, band 16q22.1 — in an intron of NFATC3.
What each result means
A/ANo copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12447640 is a single position in the genome, in or near the NFATC3 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12447640 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12447640 come from?
GWAS Catalog, Biomedicines 2022, PMID:35884923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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