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Urinary uromodulin levels

PDILT · rs12446492

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urinary uromodulin levels compared to the general population. (GWAS Catalog, J Am Soc Nephrol 2014, PMID:24578125)
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urinary uromodulin levels. (GWAS Catalog, J Am Soc Nephrol 2014, PMID:24578125)
T/T Published research associates this genotype with typical/baseline likelihood of Urinary uromodulin levels — no copies of the reported risk allele. (GWAS Catalog, J Am Soc Nephrol 2014, PMID:24578125)

Source: GWAS Catalog, J Am Soc Nephrol 2014, PMID:24578125

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs12446492

What is rs12446492?

rs12446492 is a single position in the genome, in or near the PDILT gene. Published research associates it with urinary uromodulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs12446492?

Subjects that appear in the title or abstract of the same papers as this rsID include kidneys (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs12446492 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12446492 come from?

GWAS Catalog, J Am Soc Nephrol 2014, PMID:24578125. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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