Sensitive

Small vessel stroke

JPH3 · rs12445022

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Small vessel stroke compared to the general population. (GWAS Catalog, Ann Neurol 2016, PMID:27997041)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Small vessel stroke. (GWAS Catalog, Ann Neurol 2016, PMID:27997041)

G/G Published research associates this genotype with typical/baseline likelihood of Small vessel stroke — no copies of the reported risk allele. (GWAS Catalog, Ann Neurol 2016, PMID:27997041)

Source: GWAS Catalog, Ann Neurol 2016, PMID:27997041

Questions about rs12445022

What is rs12445022?

rs12445022 is a single position in the genome, in or near the JPH3 gene. Published research associates it with small vessel stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12445022 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12445022 come from?

GWAS Catalog, Ann Neurol 2016, PMID:27997041. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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