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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 361,194 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0118 higher (95% confidence interval 0.0083-0.0153); p = 4 × 10−11.
Where it sits Chromosome 16, band 16q22.2 — in an intron of LINC02136.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Low-density lipoprotein levels (MTAG) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Low-density lipoprotein levels (MTAG).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Low-density lipoprotein levels (MTAG) compared to the general population.
Nature communications · 2022 · PMID 36376304 · open access
Questions about rs12444212
What is rs12444212?
rs12444212 is a single position in the genome, in or near the LINC02136 gene. Published research associates it with low-density lipoprotein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12444212 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12444212 come from?
GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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