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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 684,122 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.016 lower; p = 1 × 10−10.
Where it sits Chromosome 15, band 15q15.1 — in an intron of ZNF106.
What each result means
A/ANo copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2020 · PMID 32327693 · open access
Questions about rs12443246
What is rs12443246?
rs12443246 is a single position in the genome, in or near the ZNF106 gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12443246 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12443246 come from?
GWAS Catalog, Communications biology 2020, PMID:32327693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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