0 432226123223Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 449,484 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 6.38 z score higher (95% confidence interval -); p = 2 × 10−10.
Where it sits Chromosome 15, band 15q21.1 — in an intron of SEMA6D.
What each result means
C/CNo copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12442330 is a single position in the genome, in or near the SEMA6D gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12442330 linked to?
On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.
Does having rs12442330 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12442330 come from?
GWAS Catalog, Nat Genet 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 432226123223Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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