Standard

Post bronchodilator FEV1

AGPHD1 · rs12441426

Where this position leads

Condition: Pulmonary Function (Lung Capacity)

rs12441426 Condition: Pulmonary Function (Lung Capacity) Pulmonary Function (Lung Capacity) Condition rs12441426 rs12441426 AGPHD1

What the study found

Who was studied 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals.

The effect Each copy of the T allele shifted the measure 0.063 lower; p = 3 × 10−9.

How common The T allele had a frequency of about 79% in the people studied.

Where it sits Chromosome 15, band 15q25.1 — in an intron of HYKK.

What each result means

C/C No copy of the version the research linked to Post bronchodilator FEV1. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Post bronchodilator FEV1. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Post bronchodilator FEV1. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12441426

What is rs12441426?

rs12441426 is a single position in the genome, in or near the AGPHD1 gene. Published research associates it with post bronchodilator fev1. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12441426 linked to?

On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.

Does having rs12441426 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12441426 come from?

GWAS Catalog, BMC genetics 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Post bronchodilator FEV1 (rs12441426). MyGeneLog™. https://www.mygenelog.com/variants/rs12441426

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