0 6123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 26,279 European ancestry cases, 442,230 European ancestry controls, 2,590 South Asian ancestry cases, 1,720 South Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.106 lower (95% confidence interval 0.098-0.113); p = 4 × 10−18.
Where it sits Chromosome 14, band 14q13.2 — between genes, 15.6 kb from IGBP1P1.
What each result means
C/CNo copy of the version the research linked to Psoriasis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Psoriasis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of translational medicine · 2025 · PMID 39885523 · open access
Questions about rs12433497
What is rs12433497?
rs12433497 is a single position in the genome, in or near the near IGBP1P1 gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12433497 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
Does having rs12433497 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12433497 come from?
GWAS Catalog, Journal of translational medicine 2025, PMID:39885523. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 6123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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