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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,115 European ancestry individuals; replicated in 3,948 European ancestry individuals, 9,674 Chinese ancestry individuals.
The effect
The reported allele is C; the catalogue records no effect size
; p = 5 × 10−13.
How common The C allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 13, band 13q34 — between genes, 6.4 kb from LINC00676.
What each result means
C/CTwo copies of the version the research linked to Facial morphology (multitrait analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Facial morphology (multitrait analysis). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Facial morphology (multitrait analysis). This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36539420 · open access
Questions about rs12428305
What is rs12428305?
rs12428305 is a single position in the genome, in or near the near LINC00676 gene. Published research associates it with facial morphology (multitrait analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12428305 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12428305 come from?
GWAS Catalog, Nature communications 2022, PMID:36539420. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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