Standard
Permanent tooth development
HMGA2 · rs12424086
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Permanent tooth development compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Permanent tooth development.
T/T
Published research associates this genotype with typical/baseline likelihood of Permanent tooth development — no copies of the reported risk allele.
Source
Genome-wide association study identifies four loci associated with eruption of permanent teeth
Geller F,
Feenstra B,
Zhang H,
Shaffer JR,
Hansen T,
Esserlind AL,
Boyd HA,
Nohr EA,
Timpson NJ,
Fatemifar G,
Paternoster L,
Evans DM
and 10 more — show all
PLoS genetics · 2011 · PMID 21931568 · open access
Questions about rs12424086
What is rs12424086?
rs12424086 is a single position in the genome, in or near the HMGA2 gene. Published research associates it with permanent tooth development. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12424086 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12424086 come from?
GWAS Catalog, PLoS Genet 2011, PMID:21931568. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants