Sensitive

Coronary artery disease and triglyceride levels (multivariate analysis)

FBRSL1 · rs12423664

Where this position leads

Condition: Coronary Artery Disease

rs12423664 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs12423664 rs12423664 FBRSL1

What the study found

Who was studied 122,733 coronary artery disease cases, 424,528 coronary artery disease controls, 188,577 individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−8.

How common The A allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 12, band 12q24.33 — in an intron of FBRSL1.

What each result means

A/A Two copies of the version the research linked to Coronary artery disease and triglyceride levels (multivariate analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Coronary artery disease and triglyceride levels (multivariate analysis). That is a smaller link than two copies.
G/G No copy of the version the research linked to Coronary artery disease and triglyceride levels (multivariate analysis). This is the starting point the study compared everyone against.
Source

Questions about rs12423664

What is rs12423664?

rs12423664 is a single position in the genome, in or near the FBRSL1 gene. Published research associates it with coronary artery disease and triglyceride levels (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12423664 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs12423664 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12423664 come from?

GWAS Catalog, Circ Genom Precis Med 2018, PMID:30525989. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery disease and triglyceride levels (multivariate analysis) (rs12423664). MyGeneLog™. https://www.mygenelog.com/variants/rs12423664

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