Standard

Diastolic blood pressure

near OR5W2 · rs12418343

Where this position leads

Condition: Blood Pressure

rs12418343 Condition: Blood Pressure Blood Pressure Condition rs12418343 rs12418343 near OR5W2

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.183 lower (95% confidence interval 0.12-0.24); p = 4 × 10−9.

Where it sits Chromosome 11, band 11q12.1 — between genes, 5.3 kb from OR5W2.

What each result means

A/A Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
C/C No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs12418343

What is rs12418343?

rs12418343 is a single position in the genome, in or near the near OR5W2 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12418343 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs12418343 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12418343 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs12418343). MyGeneLog™. https://www.mygenelog.com/variants/rs12418343

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