0 1411219Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple1Others9Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 327,435 European ancestry individuals, 5,845 African ancestry individuals, 6,425 South Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0606 higher (95% confidence interval 0.051-0.07); p = 6 × 10−38.
Where it sits Chromosome 11, band 11p15.2 — inside PSMA1.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Vitamin D levels — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Vitamin D levels.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Vitamin D levels compared to the general population.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs12417557
What is rs12417557?
rs12417557 is a single position in the genome, in or near the PSMA1 gene. Published research associates it with vitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12417557 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs12417557 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12417557 come from?
GWAS Catalog, Nat Genet 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1411219Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple1Others9Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Vitamin D levels (rs12417557). MyGeneLog™. https://www.mygenelog.com/variants/rs12417557