Standard

Diastolic blood pressure

NT5C2 · rs12414028

Where this position leads

Condition: Blood Pressure

rs12414028 Condition: Blood Pressure Blood Pressure Condition rs12414028 rs12414028 NT5C2

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.526 lower (95% confidence interval 0.45-0.6); p = 2 × 10−45.

Where it sits Chromosome 10, band 10q24.33 — inside NT5C2.

What each result means

A/A Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs12414028

What is rs12414028?

rs12414028 is a single position in the genome, in or near the NT5C2 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12414028 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs12414028 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12414028 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Diastolic blood pressure (rs12414028). MyGeneLog™. https://www.mygenelog.com/variants/rs12414028

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