near COL11A1 · rs1241172
Where this position leads
Condition: Celiac Disease
What the study found
Who was studied 47,745 European ancestry individuals.
The effect Each copy of the C allele shifted the measure 0.0701 higher (95% confidence interval 0.051-0.089); p = 4 × 10−15.
How common The C allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 1, band 1p21.1 — between genes, 42.8 kb from COL11A1.
rs1241172 is a single position in the genome, in or near the near COL11A1 gene. Published research associates it with amy1a or amy1b or amy1c protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
AMY1A or AMY1B or AMY1C protein levels (rs1241172). MyGeneLog™. https://www.mygenelog.com/variants/rs1241172