Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP
PLA2G2E · rs12408941
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 6,692 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.79 lower (95% confidence interval 0.63-0.95); p = 2 × 10−31.
How common The A allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 1, band 1p36.13 — between genes, 12 kb from RN7SL304P.
What each result means
A/ATwo copies of the version the research linked to Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP. This is the starting point the study compared everyone against.
Arteriosclerosis, thrombosis, and vascular biology · 2019 · PMID 31070471
Questions about rs12408941
What is rs12408941?
rs12408941 is a single position in the genome, in or near the PLA2G2E gene. Published research associates it with group iia secretory phospholipase a2 levels in individuals with elevated hscrp. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12408941 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12408941 come from?
GWAS Catalog, Arteriosclerosis, thrombosis, and vascular biology 2019, PMID:31070471. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP (rs12408941). MyGeneLog™. https://www.mygenelog.com/variants/rs12408941