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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,686 Sub-Saharan African ancestry cases, 3,217 Sub-Saharan African ancestry controls, 2,013 East Asian ancestry cases, 2,701 East Asian ancestry controls.
The effect
Each copy of the A allele carried 1.51 times the odds of Esophageal squamous cell carcinoma (95% confidence interval 1.42-1.6); p = 9 × 10−10.
Where it sits Chromosome 9, band 9q22.31 — between genes, 2.2 kb from Y_RNA.
What each result means
A/ATwo copies of the version the research linked to Esophageal squamous cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Esophageal squamous cell carcinoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Esophageal squamous cell carcinoma. This is the starting point the study compared everyone against.
American journal of human genetics · 2023 · PMID 37673066
Questions about rs12379660
What is rs12379660?
rs12379660 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with esophageal squamous cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12379660 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12379660 come from?
GWAS Catalog, American journal of human genetics 2023, PMID:37673066. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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