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Platelet count during first trimester of pregnancy

FOCAD · rs12379622

What the study found

Who was studied 72,816 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0452 higher (95% confidence interval 0.031-0.059); p = 2 × 10−10.

How common The A allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 9, band 9p21.3 — in an intron of FOCAD.

What each result means

A/A Two copies of the version the research linked to Platelet count during first trimester of pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Platelet count during first trimester of pregnancy. That is a smaller link than two copies.
G/G No copy of the version the research linked to Platelet count during first trimester of pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs12379622

What is rs12379622?

rs12379622 is a single position in the genome, in or near the FOCAD gene. Published research associates it with platelet count during first trimester of pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12379622 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12379622 come from?

GWAS Catalog, Blood 2024, PMID:38064665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet count during first trimester of pregnancy (rs12379622). MyGeneLog™. https://www.mygenelog.com/variants/rs12379622

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