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Male-pattern baldness

MAPT-AS1 · rs12373124

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the C allele shifted the measure 0.08 lower; p = 1 × 10−27.

Where it sits Chromosome 17, band 17q21.31 — a synonymous change in MAPT-AS1.

What each result means

C/C Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
T/T No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
Source

Questions about rs12373124

What is rs12373124?

rs12373124 is a single position in the genome, in or near the MAPT-AS1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12373124 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12373124 come from?

GWAS Catalog, PLoS genetics 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs12373124). MyGeneLog™. https://www.mygenelog.com/variants/rs12373124

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