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Fornix white matter microstructure (intra-cellular volume fraction)

near NUAK1 · rs12369969

What the study found

Who was studied 30,832 British ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 3 × 10−9.

Where it sits Chromosome 12, band 12q23.3 — between genes, 13.9 kb from NUAK1.

What each result means

C/C No copy of the version the research linked to Fornix white matter microstructure (intra-cellular volume fraction). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Fornix white matter microstructure (intra-cellular volume fraction). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Fornix white matter microstructure (intra-cellular volume fraction). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12369969

What is rs12369969?

rs12369969 is a single position in the genome, in or near the near NUAK1 gene. Published research associates it with fornix white matter microstructure (intra-cellular volume fraction). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12369969 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12369969 come from?

GWAS Catalog, Translational psychiatry 2023, PMID:37236919. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Fornix white matter microstructure (intra-cellular volume fraction) (rs12369969). MyGeneLog™. https://www.mygenelog.com/variants/rs12369969

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