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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 438,351 Non-Finnish European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0219 higher (95% confidence interval 0.016-0.028); p = 5 × 10−14.
How common The T allele had a frequency of about 86% in the people studied.
Where it sits Chromosome 12, band 12p12.1 — between genes, 24.6 kb from KNOP1P1.
What each result means
C/CNo copy of the version the research linked to Telomere length (principal component 1). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Telomere length (principal component 1). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Telomere length (principal component 1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2024 · PMID 39192095 · open access
Questions about rs12369950
What is rs12369950?
rs12369950 is a single position in the genome, in or near the near KNOP1P1 gene. Published research associates it with telomere length (principal component 1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12369950 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12369950 come from?
GWAS Catalog, Nature genetics 2024, PMID:39192095. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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