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Who was studied 396,077 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.291 lower (95% confidence interval 0.2-0.38); p = 5 × 10−10.
How common The A allele had a frequency of about 27% in the people studied.
Where it sits Chromosome 12, band 12p13.2 — in an intron of DUSP16.
What each result means
A/ATwo copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Scientific reports · 2022 · PMID 35879408 · open access
Questions about rs12368847
What is rs12368847?
rs12368847 is a single position in the genome, in or near the DUSP16 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12368847 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs12368847 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12368847 come from?
GWAS Catalog, Scientific reports 2022, PMID:35879408. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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