Standard

systolic blood pressure (SBP, mean, inv-normal transformed)

TNS2-AS1 · rs12368584

Where this position leads

Condition: Blood Pressure

rs12368584 Condition: Blood Pressure Blood Pressure Condition rs12368584 rs12368584 TNS2-AS1

What the study found

Who was studied 119,331 African American or Afro-Caribbean individuals, 57,988 Hispanic or Latin American individuals, 6,420 East Asian ancestry individuals, 425,740 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0188 lower (95% confidence interval 0.013-0.024); p = 3 × 10−11.

How common The C allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 12, band 12q13.13 — in an intron of TNS2-AS1.

What each result means

C/C Two copies of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). That is a smaller link than two copies.
T/T No copy of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). This is the starting point the study compared everyone against.
Source

Questions about rs12368584

What is rs12368584?

rs12368584 is a single position in the genome, in or near the TNS2-AS1 gene. Published research associates it with systolic blood pressure (sbp, mean, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12368584 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs12368584 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12368584 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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systolic blood pressure (SBP, mean, inv-normal transformed) (rs12368584). MyGeneLog™. https://www.mygenelog.com/variants/rs12368584

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