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Who was studied 327,435 European ancestry individuals, 5,845 African ancestry individuals, 6,425 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0489 higher (95% confidence interval 0.036-0.062); p = 6 × 10−13.
Where it sits Chromosome 11, band 11p15.2 — between genes, 1.6 kb from SPON1-AS1.
What each result means
A/ANo copy of the version the research linked to Vitamin D levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Vitamin D levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Vitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs12364277
What is rs12364277?
rs12364277 is a single position in the genome, in or near the near SPON1-AS1 gene. Published research associates it with vitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12364277 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs12364277 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12364277 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 61212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Vitamin D levels (rs12364277). MyGeneLog™. https://www.mygenelog.com/variants/rs12364277