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Volume of right cortico-amygdaloid transition area

ITGA8 · rs12359169

What the study found

Who was studied 16,899 European ancestry males, 2,397 East Asian ancestry males.

The effect Each copy of the C allele shifted the measure 0.0551 lower (95% confidence interval 0.037-0.074); p = 6 × 10−9.

How common The C allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 10, band 10p13 — in an intron of ITGA8.

What each result means

C/C Two copies of the version the research linked to Volume of right cortico-amygdaloid transition area. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Volume of right cortico-amygdaloid transition area. That is a smaller link than two copies.
T/T No copy of the version the research linked to Volume of right cortico-amygdaloid transition area. This is the starting point the study compared everyone against.
Source

Questions about rs12359169

What is rs12359169?

rs12359169 is a single position in the genome, in or near the ITGA8 gene. Published research associates it with volume of right cortico-amygdaloid transition area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12359169 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12359169 come from?

GWAS Catalog, Nature genetics 2025, PMID:40097784. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Volume of right cortico-amygdaloid transition area (rs12359169). MyGeneLog™. https://www.mygenelog.com/variants/rs12359169

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