Standard

Body mass index

near MIR1915HG · rs12357321

Where this position leads

Condition: Childhood Body Mass Index

rs12357321 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs12357321 rs12357321 near MIR1915…

What the study found

Who was studied 342,566 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0191 higher (95% confidence interval 0.014-0.024); p = 3 × 10−13.

Where it sits Chromosome 10, band 10p12.31 — between genes, 4.3 kb from MIR1915HG.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index.
G/G Published research associates this genotype with typical/baseline likelihood of Body mass index — no copies of the reported risk allele.
Source

Questions about rs12357321

What is rs12357321?

rs12357321 is a single position in the genome, in or near the near MIR1915HG gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12357321 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs12357321 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12357321 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs12357321). MyGeneLog™. https://www.mygenelog.com/variants/rs12357321

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