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Multiple inositol polyphosphate phosphatase 1 levels

MINPP1 · rs12356259

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.121 lower (95% confidence interval 0.096-0.146); p = 3 × 10−20.

How common The A allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 10, band 10q23.2 — in an intron of MINPP1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Multiple inositol polyphosphate phosphatase 1 levels compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Multiple inositol polyphosphate phosphatase 1 levels.
T/T Published research associates this genotype with typical/baseline likelihood of Multiple inositol polyphosphate phosphatase 1 levels — no copies of the reported risk allele.
Source

Questions about rs12356259

What is rs12356259?

rs12356259 is a single position in the genome, in or near the MINPP1 gene. Published research associates it with multiple inositol polyphosphate phosphatase 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12356259 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12356259 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Multiple inositol polyphosphate phosphatase 1 levels (rs12356259). MyGeneLog™. https://www.mygenelog.com/variants/rs12356259

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