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Who was studied 39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals.
The effect
The reported allele is C; the catalogue records no effect size
; p = 3 × 10−78.
How common The C allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 9, band 9q33.3 — between genes, 15.7 kb from LHX2.
What each result means
C/CTwo copies of the version the research linked to Blond vs. brown/black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Blond vs. brown/black hair color. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Blond vs. brown/black hair color. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 30531825 · open access
Questions about rs12344562
What is rs12344562?
rs12344562 is a single position in the genome, in or near the LHX2 gene. Published research associates it with blond vs. brown/black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12344562 linked to?
On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.
Does having rs12344562 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12344562 come from?
GWAS Catalog, Nature communications 2018, PMID:30531825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 102215Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others5Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Blond vs. brown/black hair color (rs12344562). MyGeneLog™. https://www.mygenelog.com/variants/rs12344562