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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 642,173 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 1 × 10−15.
How common The A allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 9, band 9q21.2 — in the 3′ untranslated region of VPS13A.
What ClinVar records
ClassificationBenign for VPS13A-related neurodegenerative disease, Gastric cancer, Uterine carcinosarcoma, Thyroid cancer, nonmedullary, 1, Malignant tumor of esophagus and 1 more; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 4 submitters), last evaluated 2018-07-17.
ClinVar record 367437NM_033305.3(VPS13A):c.*222G>A
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Mean corpuscular hemoglobin concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Mean corpuscular hemoglobin concentration. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Mean corpuscular hemoglobin concentration. This is the starting point the study compared everyone against.
rs12343797 is a single position in the genome, in or near the VPS13A gene. Published research associates it with mean corpuscular hemoglobin concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12343797 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12343797 come from?
GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mean corpuscular hemoglobin concentration (rs12343797). MyGeneLog™. https://www.mygenelog.com/variants/rs12343797