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Fasting plasma glucose

KANK1 · rs12341226

What the study found

Who was studied 56,912 Chinese ancestry females; replicated in up to 20,026 East Asian ancestry females.

The effect Each copy of the A allele shifted the measure 0.083 lower (95% confidence interval 0.069-0.097); p = 1 × 10−30.

Where it sits Chromosome 9, band 9p24.3 — in an intron of KANK1.

What each result means

A/A Two copies of the version the research linked to Fasting plasma glucose. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Fasting plasma glucose. That is a smaller link than two copies.
G/G No copy of the version the research linked to Fasting plasma glucose. This is the starting point the study compared everyone against.
Source

Questions about rs12341226

What is rs12341226?

rs12341226 is a single position in the genome, in or near the KANK1 gene. Published research associates it with fasting plasma glucose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12341226 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12341226 come from?

GWAS Catalog, Nature communications 2025, PMID:40325049. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Fasting plasma glucose (rs12341226). MyGeneLog™. https://www.mygenelog.com/variants/rs12341226

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