Who was studied 20,016 European ancestry cases, 380,433 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−13.
How common The A allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 8, band 8q24.13 — between genes, 42.5 kb from LINC02964.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Eczema compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Eczema.
G/GPublished research associates this genotype with typical/baseline likelihood of Eczema — no copies of the reported risk allele.
Nature communications · 2021 · PMID 34785669 · open access
Questions about rs12334935
What is rs12334935?
rs12334935 is a single position in the genome, in or near the near LINC02964 gene. Published research associates it with eczema. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12334935 linked to?
On MyGeneLog this position is linked to Hay Fever And/or Eczema. The research behind each link, and its sources, are set out on that condition page.
Does having rs12334935 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12334935 come from?
GWAS Catalog, Nature communications 2021, PMID:34785669. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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