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Body mass index z-score

TROAP-AS1 · rs12313488

What the study found

Who was studied 70,636 European ancestry children, 5,040 African American children, 8,103 Hispanic / Latino children, 176 East Asian ancestry children, 630 Other admixed ancestry children, 146 American Indian / Alaskan Native ancestry children, 109 children.

The effect Each copy of the A allele shifted the measure 0.0345 lower (95% confidence interval 0.023-0.046); p = 1 × 10−8.

How common The A allele had a frequency of about 70% in the people studied.

Where it sits Chromosome 12, band 12q13.12 — in an intron of TROAP-AS1.

What each result means

A/A Two copies of the version the research linked to Body mass index z-score. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body mass index z-score. That is a smaller link than two copies.
G/G No copy of the version the research linked to Body mass index z-score. This is the starting point the study compared everyone against.
Source

Questions about rs12313488

What is rs12313488?

rs12313488 is a single position in the genome, in or near the TROAP-AS1 gene. Published research associates it with body mass index z-score. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12313488 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12313488 come from?

GWAS Catalog, HGG advances 2025, PMID:39885687. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index z-score (rs12313488). MyGeneLog™. https://www.mygenelog.com/variants/rs12313488

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