SOX5 · rs12310519
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 29,531 European ancestry cases, 128,494 European ancestry controls; replicated in 50,915 British ancestry cases, 232,837 British ancestry controls.
The effect Each copy of the T allele carried 1.07 times the odds of Chronic back pain (95% confidence interval 1.05-1.09); p = 5 × 10−19.
How common The T allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 12, band 12p12.1 — in an intron of SOX5.
rs12310519 is a single position in the genome, in or near the SOX5 gene. Published research associates it with chronic back pain. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS Genet 2018, PMID:30261039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Chronic back pain (rs12310519). MyGeneLog™. https://www.mygenelog.com/variants/rs12310519