Standard
Thyroid peroxidase antibody levels
MAG13 · rs1230666
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Thyroid peroxidase antibody levels compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Thyroid peroxidase antibody levels.
G/G
Published research associates this genotype with typical/baseline likelihood of Thyroid peroxidase antibody levels — no copies of the reported risk allele.
Source
Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease
Medici M,
Porcu E,
Pistis G,
Teumer A,
Brown SJ,
Jensen RA,
Rawal R,
Roef GL,
Plantinga TS,
Vermeulen SH,
Lahti J,
Simmonds MJ
and 106 more — show all
Husemoen LL,
Freathy RM,
Shields BM,
Pietzner D,
Nagy R,
Broer L,
Chaker L,
Korevaar TI,
Plia MG,
Sala C,
Völker U,
Richards JB,
Sweep FC,
Gieger C,
Corre T,
Kajantie E,
Thuesen B,
Taes YE,
Visser WE,
Hattersley AT,
Kratzsch J,
Hamilton A,
Li W,
Homuth G,
Lobina M,
Mariotti S,
Soranzo N,
Cocca M,
Nauck M,
Spielhagen C,
Ross A,
Arnold A,
van de Bunt M,
Liyanarachchi S,
Heier M,
Grabe HJ,
Masciullo C,
Galesloot TE,
Lim EM,
Reischl E,
Leedman PJ,
Lai S,
Delitala A,
Bremner AP,
Philips DI,
Beilby JP,
Mulas A,
Vocale M,
Abecasis G,
Forsen T,
James A,
Widen E,
Hui J,
Prokisch H,
Rietzschel EE,
Palotie A,
Feddema P,
Fletcher SJ,
Schramm K,
Rotter JI,
Kluttig A,
Radke D,
Traglia M,
Surdulescu GL,
He H,
Franklyn JA,
Tiller D,
Vaidya B,
de Meyer T,
Jørgensen T,
Eriksson JG,
O'Leary PC,
Wichmann E,
Hermus AR,
Psaty BM,
Ittermann T,
Hofman A,
Bosi E,
Schlessinger D,
Wallaschofski H,
Pirastu N,
Aulchenko YS,
de la Chapelle A,
Netea-Maier RT,
Gough SC,
Meyer Zu Schwabedissen H,
Frayling TM,
Kaufman JM,
Linneberg A,
Räikkönen K,
Smit JW,
Kiemeney LA,
Rivadeneira F,
Uitterlinden AG,
Walsh JP,
Meisinger C,
den Heijer M,
Visser TJ,
Spector TD,
Wilson SG,
Völzke H,
Cappola A,
Toniolo D,
Sanna S,
Naitza S,
Peeters RP
PLoS genetics · 2014 · PMID 24586183 · open access
Questions about rs1230666
What is rs1230666?
rs1230666 is a single position in the genome, in or near the MAG13 gene. Published research associates it with thyroid peroxidase antibody levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1230666 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1230666 come from?
GWAS Catalog, PLoS Genet 2014, PMID:24586183. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants