Sensitive
Squamous cell carcinoma
SLC17A8 · rs12296850
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Squamous cell carcinoma compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Squamous cell carcinoma.
G/G
Published research associates this genotype with typical/baseline likelihood of Squamous cell carcinoma — no copies of the reported risk allele.
Source
Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in han chinese
Dong J,
Jin G,
Wu C,
Guo H,
Zhou B,
Lv J,
Lu D,
Shi Y,
Shu Y,
Xu L,
Chu M,
Wang C
and 37 more — show all
Zhang R,
Dai J,
Jiang Y,
Yu D,
Ma H,
Zhao X,
Yin Z,
Yang L,
Li Z,
Deng Q,
Cao S,
Qin Z,
Gong J,
Sun C,
Wang J,
Wu W,
Zhou G,
Chen H,
Guan P,
Chen Y,
Liu X,
Liu L,
Xu P,
Han B,
Bai C,
Zhao Y,
Zhang H,
Yan Y,
Liu J,
Amos CI,
Chen F,
Tan W,
Jin L,
Wu T,
Hu Z,
Lin D,
Shen H
PLoS genetics · 2013 · PMID 23341777 · open access
Questions about rs12296850
What is rs12296850?
rs12296850 is a single position in the genome, in or near the SLC17A8 gene. Published research associates it with squamous cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12296850 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12296850 come from?
GWAS Catalog, PLoS Genet 2013, PMID:23341777. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants