0 402217223219Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others19Total40Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 833 Han Chinese ancestry cases, 3,094 Han Chinese ancestry controls; replicated in 2,223 Han Chinese ancestry cases, 6,409 Han Chinese ancestry controls.
The effect
Each copy of the A allele carried 1.28 times the odds of Squamous cell carcinoma (95% confidence interval 1.19-1.39); p = 1 × 10−10.
How common The A allele had a frequency of about 74% in the people studied.
Where it sits Chromosome 12, band 12q23.1 — between genes, 4.3 kb from SLC17A8.
What each result means
A/ATwo copies of the version the research linked to Squamous cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Squamous cell carcinoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Squamous cell carcinoma. This is the starting point the study compared everyone against.
PLoS genetics · 2013 · PMID 23341777 · open access
Questions about rs12296850
What is rs12296850?
rs12296850 is a single position in the genome, in or near the SLC17A8 gene. Published research associates it with squamous cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12296850 linked to?
On MyGeneLog this position is linked to Lung Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs12296850 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12296850 come from?
GWAS Catalog, PLoS Genet 2013, PMID:23341777. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 402217223219Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others19Total40Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.