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Who was studied 9,747 European ancestry cases, 14,278 European ancestry controls.
The effect
Each copy of the A allele carried 1.19 times the odds of Bipolar disorder; p = 1 × 10−9.
Where it sits Chromosome 11, band 11q14.1 — in an intron of TENM4.
What each result means
A/ATwo copies of the version the research linked to Bipolar disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Bipolar disorder. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Bipolar disorder. This is the starting point the study compared everyone against.
rs12290811 is a single position in the genome, in or near the ODZ4 gene. Published research associates it with bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12290811 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs12290811 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12290811 come from?
GWAS Catalog, Nat Commun 2014, PMID:24618891. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 4422126123124Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others24Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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