Standard

Educational attainment (MTAG)

IGSF9B · rs12273435

Where this position leads

Condition: Educational Attainment

rs12273435 Condition: Educational Attainment Educational Attainment Condition rs12273435 rs12273435 IGSF9B

What the study found

Who was studied 1,311,438 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0136 lower (95% confidence interval 0.01-0.017); p = 6 × 10−17.

How common The A allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 11, band 11q25 — in an intron of IGSF9B.

What each result means

A/A Two copies of the version the research linked to Educational attainment (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Educational attainment (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Educational attainment (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs12273435

What is rs12273435?

rs12273435 is a single position in the genome, in or near the IGSF9B gene. Published research associates it with educational attainment (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12273435 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs12273435 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12273435 come from?

GWAS Catalog, Nat Genet 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Educational attainment (MTAG) (rs12273435). MyGeneLog™. https://www.mygenelog.com/variants/rs12273435

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