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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied at least 19,099 European ancestry cases, at least 34,194 European ancestry controls; replicated in 2,726 European ancestry cases, 16,299 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0984 higher (95% confidence interval 0.07-0.127); p = 2 × 10−11.
How common The T allele had a frequency of about 77% in the people studied.
Where it sits Chromosome 10, band 10q25.1 — in an intron of SORCS3.
What each result means
C/CNo copy of the version the research linked to Attention deficit hyperactivity disorder (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Attention deficit hyperactivity disorder (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Attention deficit hyperactivity disorder (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Translational psychiatry · 2021 · PMID 33479212 · open access
Questions about rs12265655
What is rs12265655?
rs12265655 is a single position in the genome, in or near the SORCS3 gene. Published research associates it with attention deficit hyperactivity disorder (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12265655 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12265655 come from?
GWAS Catalog, Translational psychiatry 2021, PMID:33479212. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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