0 24191238Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI9Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 170,672 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0382 lower (95% confidence interval 0.03-0.046); p = 7 × 10−20.
How common The T allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 10, band 10p15.3 — in an intron of LARP4B.
What each result means
C/CNo copy of the version the research linked to Neutrophil percentage of granulocytes. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Neutrophil percentage of granulocytes. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Neutrophil percentage of granulocytes. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12259338 is a single position in the genome, in or near the LARP4B gene. Published research associates it with neutrophil percentage of granulocytes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12259338 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs12259338 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12259338 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 24191238Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI9Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others8Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Neutrophil percentage of granulocytes (rs12259338). MyGeneLog™. https://www.mygenelog.com/variants/rs12259338