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VCAM1 protein levels

near VCAM1 · rs12240047

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0844 lower (95% confidence interval 0.071-0.098); p = 7 × 10−39.

How common The C allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 1, band 1p21.2 — between genes, 3.9 kb from VCAM1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of VCAM1 protein levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with VCAM1 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of VCAM1 protein levels — no copies of the reported risk allele.
Source

Questions about rs12240047

What is rs12240047?

rs12240047 is a single position in the genome, in or near the near VCAM1 gene. Published research associates it with vcam1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12240047 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12240047 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

VCAM1 protein levels (rs12240047). MyGeneLog™. https://www.mygenelog.com/variants/rs12240047

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