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Neuroticism

ELAVL2 · rs12236195

Where this position leads

Condition: Neuroticism

rs12236195 Condition: Neuroticism Neuroticism Condition rs12236195 rs12236195 ELAVL2

What the study found

Who was studied 523,783 European ancestry individuals; replicated in 59,206 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0108 higher (95% confidence interval 0.0071-0.0144); p = 1 × 10−8.

How common The T allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 9, band 9p21.3 — in an intron of ELAVL2.

What each result means

C/C No copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12236195

What is rs12236195?

rs12236195 is a single position in the genome, in or near the ELAVL2 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12236195 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs12236195 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12236195 come from?

GWAS Catalog, Nat Genet 2019, PMID:30643256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuroticism (rs12236195). MyGeneLog™. https://www.mygenelog.com/variants/rs12236195

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