near PLXDC2 · rs12219125
Where this position leads
Condition: Diabetic Retinopathy
What the study found
Who was studied 174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 9 × 10−9.
Where it sits Chromosome 10, band 10p12.31 — between genes, 14.3 kb from PLXDC2.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs12219125 is a single position in the genome, in or near the near PLXDC2 gene. Published research associates it with diabetic retinopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Diabetic Retinopathy. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Ophthalmology 2011, PMID:21310492. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Diabetic retinopathy (rs12219125). MyGeneLog™. https://www.mygenelog.com/variants/rs12219125