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Who was studied 5,764 African American or Afro-Caribbean cases, 42,247 African American or Afro-Caribbean controls, 28,645 European ancestry cases, 264,556 European ancestry controls, 1,678 Hispanic or Latin American cases, 24,750 Hispanic or Latin American controls.
The effect
Each copy of the T allele shifted the measure 0.0911 lower (95% confidence interval 0.067-0.116); p = 4 × 10−11.
How common The T allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 6, band 6q21 — in an intron of SESN1.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Prostate cancer — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Prostate cancer.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Prostate cancer compared to the general population.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs12213664
What is rs12213664?
rs12213664 is a single position in the genome, in or near the SESN1 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12213664 linked to?
On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs12213664 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12213664 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Prostate cancer (rs12213664). MyGeneLog™. https://www.mygenelog.com/variants/rs12213664