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CD24 on transitional B cell

LINC02532 · rs12206866

What the study found

Who was studied 3,656 Sardinian (founder/genetic isolate) ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.446 lower (95% confidence interval 0.34-0.55); p = 1 × 10−16.

How common The T allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 6, band 6q21 — in an intron of LINC02532.

What each result means

C/C No copy of the version the research linked to CD24 on transitional B cell. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to CD24 on transitional B cell. That is a smaller link than two copies.
T/T Two copies of the version the research linked to CD24 on transitional B cell. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12206866

What is rs12206866?

rs12206866 is a single position in the genome, in or near the LINC02532 gene. Published research associates it with cd24 on transitional b cell. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12206866 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12206866 come from?

GWAS Catalog, Nature genetics 2020, PMID:32929287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CD24 on transitional B cell (rs12206866). MyGeneLog™. https://www.mygenelog.com/variants/rs12206866

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